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MEGUIAR'S G192 User Manual

Page 10

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G192, Ultimate Polish (24-05B): G192

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Page: 10 of 18

1,125
mg/kg/day

organogenesis

Glycerin

Ingestion

Not toxic to female reproduction

Rat

NOAEL
2,000
mg/kg/day

2 generation

Glycerin

Ingestion

Not toxic to male reproduction

Rat

NOAEL
2,000
mg/kg/day

2 generation

Glycerin

Ingestion

Not toxic to development

Rat

NOAEL
2,000
mg/kg/day

2 generation

Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one

Ingestion

Not toxic to female reproduction

Rat

NOAEL 10
mg/kg/day

2 generation

Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one

Ingestion

Not toxic to male reproduction

Rat

NOAEL 10
mg/kg/day

2 generation

Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one

Ingestion

Not toxic to development

Rat

NOAEL 15
mg/kg/day

during

organogenesis

Target Organ(s)

Specific Target Organ Toxicity - single exposure

Name

Route

Target Organ(s)

Value

Species

Test result

Exposure
Duration

Distillates (petroleum),
hydrotreated middle

Inhalation

central nervous
system depression |
respiratory irritation

Some positive data exist, but the
data are not sufficient for
classification

Not
available

NOAEL NA

Distillates (petroleum),
hydrotreated middle

Ingestion

central nervous
system depression

May cause drowsiness or
dizziness

Not
available

NOAEL NA

Solvent naphtha
(petroleum), medium
aliphatic

Inhalation

central nervous
system depression

May cause drowsiness or
dizziness

Human
and
animal

NOAEL Not
available

Solvent naphtha
(petroleum), medium
aliphatic

Inhalation

respiratory irritation

Some positive data exist, but the
data are not sufficient for
classification

NOAEL Not
available

Solvent naphtha
(petroleum), medium
aliphatic

Inhalation

nervous system

Some positive data exist, but the
data are not sufficient for
classification

Dog

NOAEL 6.5
mg/l

4 hours

Mixture of 5-chloro-2-
methyl-2H-isothiazol-3-
one and 2-methyl-2H-
isothiazol-3-one

Inhalation

respiratory irritation

Some positive data exist, but the
data are not sufficient for
classification

similar
health
hazards

NOAEL Not
available

Specific Target Organ Toxicity - repeated exposure

Name

Route

Target Organ(s)

Value

Species

Test result

Exposure
Duration

Aluminium oxide

Inhalation

pneumoconiosis

Some positive data exist, but the
data are not sufficient for
classification

Human

NOAEL Not
available

occupational
exposure

Solvent naphtha
(petroleum), medium
aliphatic

Inhalation

nervous system

Some positive data exist, but the
data are not sufficient for
classification

Rat

LOAEL 4.6
mg/l

6 months

Solvent naphtha
(petroleum), medium
aliphatic

Inhalation

kidney and/or
bladder

Some positive data exist, but the
data are not sufficient for
classification

Rat

LOAEL 1.9
mg/l

13 weeks

Solvent naphtha
(petroleum), medium
aliphatic

Inhalation

respiratory system

Some positive data exist, but the
data are not sufficient for
classification

Multiple
animal
species

NOAEL 0.6
mg/l

90 days

Aluminium oxide

Inhalation

pulmonary fibrosis

Some positive data exist, but the
data are not sufficient for
classification

Human

NOAEL Not
available

occupational
exposure

Solvent naphtha
(petroleum), medium
aliphatic

Inhalation

bone, teeth, nails,
and/or hair | blood |
liver | muscles

All data are negative

Rat

NOAEL 5.6
mg/l

12 weeks

Solvent naphtha

Inhalation

heart

All data are negative

Multiple

NOAEL 1.3

90 days