MEGUIAR'S A33 - Manual (Page 8)

A33, Quik Detailer (19-187B): A3316, A3332
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animal
species 1,230
mg/kg/day organogenesis
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to female reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to male reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to development Rat NOAEL 15
mg/kg/day during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
1-propoxypropan-2-ol Inhalation central nervous
system depression May cause drowsiness or
dizziness Multiple
animal
species LOAEL 10.8
mg/l 6 hours
1-propoxypropan-2-ol Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification NOAEL Not
available
1-propoxypropan-2-ol Ingestion central nervous
system depression May cause drowsiness or
dizziness Rat LOAEL
1,770 mg/kg not applicable
Propane-1,2-diol Ingestion central nervous
system depression May cause drowsiness or
dizziness Human NOAEL Not
available poisoning
and/or abuse
Mixture of 5-chloro-2-
methyl-2H-isothiazol-3-
one and 2-methyl-2H-
isothiazol-3-one Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification similar
health
hazards NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
1-propoxypropan-2-ol Inhalation liver | kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 9.5
mg/l 11 days
Propane-1,2-diol Ingestion hematopoietic
system Some positive data exist, but the
data are not sufficient for
classification Multiple
animal
species NOAEL
1,370
mg/kg/day 117 days
Propane-1,2-diol Ingestion kidney and/or
bladder All data are negative Dog NOAEL
5,000
mg/kg/day 104 weeks
Aspiration Hazard
Name Value
Please contact the address or phone number listed on the first page of the SDS for additional toxicological information
on this material and/or its components.
SECTION 12: Ecological information
The information below may not agree with the EU material classification in Section 2 and/or the ingredient
classifications in Section 3 if specific ingredient classifications are mandated by a competent authority. In addition,
statements and data presented in Section 12 are based on UN GHS calculation rules and classifications derived from
3M assessments.
12.1. Toxicity
No product test data available.