MEGUIAR'S M16 - Manual (Page 9)

M16, Mirror Glaze Professional Paste Wax (Original Formula): M1611
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Germ Cell Mutagenicity
Name Route Value
Naphtha (petroleum), hydrotreated heavy In vivo Not mutagenic
Naphtha (petroleum), hydrotreated heavy In Vitro Some positive data exist, but the data are not
sufficient for classification
Distillates (petroleum), hydrotreated light In Vitro Not mutagenic
Carcinogenicity
Name Route Species Value
Naphtha (petroleum), hydrotreated heavy Dermal Mouse Some positive data exist, but the data are not
sufficient for classification
Naphtha (petroleum), hydrotreated heavy Inhalation Human
and
animal Some positive data exist, but the data are not
sufficient for classification
Distillates (petroleum), hydrotreated light Dermal Mouse Some positive data exist, but the data are not
sufficient for classification
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Naphtha (petroleum), hydrotreated heavy Inhalation Not toxic to development Rat NOAEL 2.4
mg/l during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Naphtha (petroleum),
hydrotreated heavy Inhalation central nervous
system depression May cause drowsiness or
dizziness Human
and
animal NOAEL Not
available
Naphtha (petroleum),
hydrotreated heavy Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification NOAEL Not
available
Naphtha (petroleum),
hydrotreated heavy Inhalation nervous system Some positive data exist, but the
data are not sufficient for
classification Dog NOAEL 6.5
mg/l 4 hours
Distillates (petroleum),
hydrotreated light Inhalation central nervous
system depression May cause drowsiness or
dizziness NOAEL Not
available
Distillates (petroleum),
hydrotreated light Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Naphtha (petroleum),
hydrotreated heavy Inhalation nervous system Some positive data exist, but the
data are not sufficient for
classification Rat LOAEL 4.6
mg/l 6 months
Naphtha (petroleum),
hydrotreated heavy Inhalation kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Rat LOAEL 1.9
mg/l 13 weeks
Naphtha (petroleum),
hydrotreated heavy Inhalation respiratory system Some positive data exist, but the
data are not sufficient for
classification Multiple
animal
species NOAEL 0.6
mg/l 90 days
Naphtha (petroleum),
hydrotreated heavy Inhalation bone, teeth, nails,
and/or hair | blood |
liver | muscles All data are negative Rat NOAEL 5.6
mg/l 12 weeks
Naphtha (petroleum),
hydrotreated heavy Inhalation heart All data are negative Multiple
animal
species NOAEL 1.3
mg/l 90 days