MEGUIAR'S M39 - Manual (Page 8)

M39, Heavy Duty Vinyl Cleaner (24-161B): M3916
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Glycerin Rabbit No significant irritation
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Rabbit Corrosive
Serious Eye Damage/Irritation
Name Species Value
Trisodium Phosphate Rabbit Corrosive
Glycerin Rabbit No significant irritation
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Rabbit Corrosive
Skin Sensitisation
Name Species Value
Glycerin Guinea
pig Not sensitizing
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Human
and
animal Sensitising
Photosensitisation
Name Species Value
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Human
and
animal Not sensitizing
Respiratory Sensitisation
Name Species Value
Germ Cell Mutagenicity
Name Route Value
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one In vivo Not mutagenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one In Vitro Some positive data exist, but the data are not
sufficient for classification
Carcinogenicity
Name Route Species Value
Glycerin Ingestion Mouse Some positive data exist, but the data are not
sufficient for classification
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Dermal Mouse Not carcinogenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Ingestion Rat Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Glycerin Ingestion Not toxic to female reproduction Rat NOAEL
2,000
mg/kg/day 2 generation
Glycerin Ingestion Not toxic to male reproduction Rat NOAEL
2,000
mg/kg/day 2 generation
Glycerin Ingestion Not toxic to development Rat NOAEL
2,000
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to female reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H- Ingestion Not toxic to male reproduction Rat NOAEL 10
mg/kg/day 2 generation