MEGUIAR'S M52 - Manual (Page 7)

M52, Quick Clean Marine (19-187B): M5216
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Propylene Glycol Ingestion Not mutagenic
Propylene Glycol In Vitro Some positive data exist, but the data are not
sufficient for classification
Carcinogenicity
Name Route Species Value
1-propoxypropan-2-ol No data available
Propylene Glycol Dermal Not carcinogenic
Propylene Glycol Ingestion Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure Duration
1-propoxypropan-2-
ol Inhalation Some positive
reproductive/develop
mental data exist, but
the data are not
sufficient for
classification NOEL 3.6
mg/l
Propylene Glycol Ingestion Not toxic to
reproduction and/or
development NOAEL
10,100
mg/kg/day
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target
Organ(s) Value Species Test result Exposure
Duration
1-
propoxypropa
n-2-ol Inhalation central nervous
system
depression May cause
drowsiness or
dizziness LOAEL 10.8
mg/l
1-
propoxypropa
n-2-ol Inhalation respiratory
irritation Some positive
data exist, but the
data are not
sufficient for
classification Irritation
Positive
1-
propoxypropa
n-2-ol Ingestion central nervous
system
depression May cause
drowsiness or
dizziness LOAEL 1,770
mg/kg
Propylene
Glycol No data available
Specific Target Organ Toxicity - repeated exposure
Name Route Target
Organ(s) Value Species Test result Exposure
Duration
1-
propoxypropa
n-2-ol Inhalation liver | kidney
and/or bladder Some positive
data exist, but the
data are not
sufficient for
classification LOEL 2.4 mg/l
Propylene
Glycol Ingestion hematopoietic
system Some positive
data exist, but the
data are not
sufficient for
classification LOEL 511
mg/kg/day
Propylene
Glycol Ingestion kidney and/or
bladder All data are
negative NOAEL 5,000
mg/kg/day