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MEGUIAR'S M67 User Manual

Page 8

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M67, Marine One Step Compound (19-17D): M6732

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Page: 8 of 13

Skin Sensitisation

Name

Species

Value

NUC - Naphthol Spirits

Guinea
pig

Not sensitizing

White mineral oil (petroleum)

Guinea
pig

Not sensitizing

Respiratory Sensitisation

Name

Species

Value

Germ Cell Mutagenicity

Name

Route

Value

Aluminium Oxide

In Vitro

Not mutagenic

NUC - Naphthol Spirits

In vivo

Not mutagenic

NUC - Naphthol Spirits

In Vitro

Some positive data exist, but the data are not
sufficient for classification

White mineral oil (petroleum)

In Vitro

Not mutagenic

Carcinogenicity

Name

Route

Species

Value

Aluminium Oxide

Inhalation

Rat

Not carcinogenic

NUC - Naphthol Spirits

Dermal

Mouse

Some positive data exist, but the data are not
sufficient for classification

NUC - Naphthol Spirits

Inhalation

Human
and
animal

Some positive data exist, but the data are not
sufficient for classification

White mineral oil (petroleum)

Dermal

Mouse

Not carcinogenic

White mineral oil (petroleum)

Inhalation

Multiple
animal
species

Not carcinogenic

Reproductive Toxicity

Reproductive and/or Developmental Effects

Name

Route

Value

Species

Test result

Exposure
Duration

NUC - Naphthol Spirits

Inhalation

Not toxic to development

Rat

NOAEL 2.4
mg/l

during

organogenesis

White mineral oil (petroleum)

Ingestion

Not toxic to female reproduction

Rat

NOAEL
4,350
mg/kg/day

13 weeks

White mineral oil (petroleum)

Ingestion

Not toxic to male reproduction

Rat

NOAEL
4,350
mg/kg/day

13 weeks

White mineral oil (petroleum)

Ingestion

Not toxic to development

Rat

NOAEL
4,350
mg/kg/day

during

gestation

Target Organ(s)

Specific Target Organ Toxicity - single exposure

Name

Route

Target Organ(s)

Value

Species

Test result

Exposure
Duration

NUC - Naphthol Spirits

Inhalation

central nervous
system depression

May cause drowsiness or
dizziness

Human
and
animal

NOAEL Not
available

NUC - Naphthol Spirits

Inhalation

respiratory irritation

Some positive data exist, but the
data are not sufficient for
classification

NOAEL Not
available

NUC - Naphthol Spirits

Inhalation

nervous system

Some positive data exist, but the
data are not sufficient for
classification

Dog

NOAEL 6.5
mg/l

4 hours

Specific Target Organ Toxicity - repeated exposure