MEGUIAR'S M80 User Manual
Page 9

M80, Speed Glaze (13-171C): M8001, M8032
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1-methyl-2-pyrrolidone
In vivo
Not mutagenic
1-methyl-2-pyrrolidone
In Vitro
Some positive data exist, but the data are not
sufficient for classification
Glycerin
No data available
Processed oil
In Vitro
Not mutagenic
Processed oil
In vivo
Not mutagenic
Siloxanes and silicones, di-Me
No data available
Conditioners
No data available
2-Methoxyethanol
In Vitro
Not mutagenic
2-Methoxyethanol
Inhalation
Not mutagenic
Carcinogenicity
Name
Route
Species
Value
Aluminium oxide
Inhalation
Not carcinogenic
Naphtha (petroleum), hydrotreated
heavy
Dermal
Some positive data exist, but the data
are not sufficient for classification
Naphtha (petroleum), hydrotreated
heavy
Inhalation
Some positive data exist, but the data
are not sufficient for classification
Distillates (petroleum), hydrotreated
middle
Dermal
Mouse
Some positive data exist, but the data
are not sufficient for classification
1-methyl-2-pyrrolidone
Inhalation
Rat
Not carcinogenic
Glycerin
Ingestion
Mouse
Some positive data exist, but the data
are not sufficient for classification
Processed oil
No data available
Siloxanes and silicones, di-Me
No data available
Conditioners
No data available
2-Methoxyethanol
No data available
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name
Route
Value
Species
Test result
Exposure Duration
Aluminium oxide
No data available
Naphtha (petroleum),
hydrotreated heavy
Inhalation
Not toxic to
reproduction and/or
development
NOAEL
2.356 mg/l
Distillates
(petroleum),
hydrotreated middle
No data available
1-methyl-2-
pyrrolidone
Inhalation
Some positive
developmental data
exist, but the data are
not sufficient for
classification
Rat
LOAEL 0.68
mg/l
during gestation
1-methyl-2-
pyrrolidone
Dermal
Toxic to reproduction
and/or development
NOAEL 237
mg/kg/day
1-methyl-2-
pyrrolidone
Ingestion
Toxic to female
reproduction
Rat
LOAEL 50
mg/kg/day
2 generation
1-methyl-2-
pyrrolidone
Ingestion
Toxic to male
reproduction
Rat
LOAEL 50
mg/kg/day
2 generation
1-methyl-2-
pyrrolidone
Dermal
Toxic to development
Rat
NOAEL 237
mg/kg/day
during organogenesis
1-methyl-2-
pyrrolidone
Ingestion
Toxic to reproduction
and/or development
LOAEL 50
mg/kg/day
1-methyl-2-
pyrrolidone
Ingestion
Toxic to development
Rat
NOAEL 160
mg/kg/day
2 generation
Glycerin
Ingestion
Not toxic to female
reproduction
Rat
NOAEL
2,000
mg/kg/day
2 generation
Glycerin
Ingestion
Not toxic to male
Rat
NOAEL
2 generation