MEGUIAR'S MC203 - Manual (Page 9)

MC203, Motorcycle Leather Cleaner/Conditioner (20-175A): MC20306
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Distillates (petroleum), hydrotreated middle In Vitro Some positive data exist, but the data are not
sufficient for classification
Stearic Acid In Vitro Not mutagenic
Triethanolamine In Vitro Not mutagenic
Triethanolamine In vivo Not mutagenic
Zinc oxide In Vitro Some positive data exist, but the data are not
sufficient for classification
Zinc oxide In vivo Some positive data exist, but the data are not
sufficient for classification
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one In vivo Not mutagenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one In Vitro Some positive data exist, but the data are not
sufficient for classification
Carcinogenicity
Name Route Species Value
Distillates (petroleum), hydrotreated middle Dermal Mouse Some positive data exist, but the data are not
sufficient for classification
Stearic Acid Ingestion Rat Not carcinogenic
Triethanolamine Dermal Multiple
animal
species Not carcinogenic
Triethanolamine Ingestion Mouse Some positive data exist, but the data are not
sufficient for classification
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Dermal Mouse Not carcinogenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Ingestion Rat Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Triethanolamine Ingestion Not toxic to development Mouse NOAEL
1,125
mg/kg/day during
organogenesis
Zinc oxide Ingestion Some positive
reproductive/developmental data exist,
but the data are not sufficient for
classification Multiple
animal
species NOAEL 125
mg/kg/day premating &
during
gestation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to female reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to male reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to development Rat NOAEL 15
mg/kg/day during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Distillates (petroleum),
hydrotreated middle Inhalation central nervous
system depression |
respiratory irritation Some positive data exist, but the
data are not sufficient for
classification Not
available NOAEL NA
Distillates (petroleum),
hydrotreated middle Ingestion central nervous
system depression May cause drowsiness or
dizziness Not
available NOAEL NA
Stearic Acid Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification NOAEL Not
available
Mixture of 5-chloro-2-
methyl-2H-isothiazol-3- Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for similar
health NOAEL Not
available