Bio-Rad Bio-Scale™ Mini UNOsphere SUPrA™ Affinity Cartridges - Manual (Page 7)

UNOsphere SUPrA™ medium is a chromatographic
support based on recombinant protein A. The
media are designed for process-scale purification of
monoclonal antibodies. The protein A ligand is
produced in E. coli without the use of material from
animal origin. The UNOsphere base bead is a
macroporous polymeric bead that is designed for
robust and scaleable applications. See Tables 1 and
2 on pages 4–5 for the technical description of the
product.
UNOsphere SUPrA media are built on the proven
UNOsphere base bead, which insures an easy
scale-up path for process applications. The
outstanding flow pressure performance of
UNOsphere chromatography media allow its use in
process applications without concern for exceeding
the pressure limits of the media or chromatography
system. The flow characteristics of UNOsphere
SUPrA packed in a large column format are shown
in Figure 1.
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